Integrals are the devil's handiwork. Derivatives are almost too easy, and then you get to Calc II and suddenly you're supposed to be able to do it inside out and backwards, with the help of all those dozens of identities you must now memorize. I went from an A+ in Calc I to a C- in Calc II.
Yup. I bombed calculus twice simply because I have a lot of trouble memorizing things like that. I ended up taking the sucker's way out: I took it online in a class where Mathematica was encouraged. I use derivatives and integrals pretty often now, but I've yet to need to do them by hand since.